antidepression

History of antidepressants

In Drugs, History/development on October 22, 2008 at 7:00 pm

Before the boom of psychopharmacology in the 1950s, the treatments for mood disorders were relatively limited and crude, including shock treatment, insulin coma therapy, and sleep-deprivation therapy. While we’ve come a long way from inducing insulin comas, there are now dozens of antipsychotics on the market to treat depression.

MAOIs and tricyclics were the first antidepressants developed, dating back to the 1950s. These drugs came with numerous side effects and sometimes strict regiments for taking the drugs. Because of this, researchers looked for an alternative with simliar effectiveness but fewer side effects and found this in SSRIs. Even more recently, researhcers have developed another class of drugs, serotonin-norepinephrine reuptake inhibitors (SNRIs), thought to be even more effective but with similar side effects to SSRIs.

1950-19803

1980-2000

2000s

Related material:
Types of antidepressants
Cost to the system

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